Hepatitis D – satellite virus of HBV

Hepatitis D makes the treatment of hepatitis B more difficult. The risk of liver cirrhosis is greatly increased with simultaneous HDV infection. Due to the risk of a fulminant course, monitoring of transaminases and liver synthesis performance is of particular importance in acute HDV infection. In addition to pegylated interferon-alpha, bulevirtide is also available for treatment. Phase III data on this entry inhibitor were published in the New England Journal of Medicine 2023.