Importance of vancomycin and fidaxomicin has increased

C. difficile infection (CDI) is the most common pathogen-related cause of nosocomial diarrhea, but can also occur in outpatients if risk factors are present. Due to the associated morbidity and mortality risks, there is usually an indication for specific treatment in the case of a diagnosed CDI. The use of oral antibiotics remains the most important measure, although previous antibiotic treatment is the main risk factor for the development of CDI.