Precision Neurology

Neuroscience has made a huge leap in knowledge in recent decades. New methods in genomics, epigenetics, proteomics, metabolomics, imaging and data integration make it possible to characterize diseases more precisely than is possible through purely clinical observation. The concept of “precision neurology” transfers the logic of precision medicine to the field of neurology and psychiatry. It aims to make individual profiles from molecular, structural and functional data usable for diagnosis, prognosis and therapy. This overview summarizes the principles, methods, current evidence and key challenges.