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Allergology and clinical immunology

430 posts
  • This content is machine translated Oral JAK-i in atopic dermatitis

Benefits and risks: What does the current data say?

Although there have been no recent approvals of oral JAK inhibitors (JAK-i) for atopic dermatitis (AD), some interesting study findings have been published. These shed light on the safety of...…
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  • 4 min
  • This content is machine translated Biologics for atopic dermatitis

Th2 cytokines in focus: proven and new targets

The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
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  • 7 min
  • This content is machine translated Study report

Scabies treatment: benzyl benzoate in direct comparison with permethrin

European guidelines mention permethrin, benzyl benzoate and crotamiton as topical antiscabiosa. There have been repeated reports of treatment failure with permethrin in recent years, although the causes are controversial. In...…
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  • 4 min
  • This content is machine translated Work-related asthma

When the job leads to exacerbations

Asthma attacks caused by occupational exposure are very common in adults with asthma. Although previous studies have mainly focused on occupational asthma (OA), interest in work-exacerbated ast hma (WEA) has...…
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  • 5 min
  • This content is machine translated Psoriasis

Indications of an increased risk of “leaky gut”

Psoriasis sufferers often have invisible inflammation in the small intestine along with a tendency to increased permeability of the intestinal barrier (“leaky gut”), according to recently published research from Uppsala...…
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  • 12 min
  • This content is machine translated Evidence, effectiveness and practical implications

Medicinal plants for allergic rhinitis

Allergic rhinitis is an immunologically mediated disease that occurs frequently worldwide and is caused by a type I hypersensitivity reaction (IgE-mediated) to allergenic substances. The clinical symptoms mainly include rhinorrhea...…
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  • 6 min
  • This content is machine translated Urticaria & urticaria-like exanthema

Case studies from pediatric dermatology

The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
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  • 7 min
  • This content is machine translated Moderate to severe chronic hand eczema

Delgocitinib cream – first topical pan-JAK inhibitor approved in Switzerland

In the phase III DELTA 1 and 2 studies, delgocitinib cream showed a rapid onset of efficacy – at week 16, half of the patients achieved a 75% improvement in...…
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  • 4 min
  • This content is machine translated Prurigo nodularis

Retrospective analyses of large data sets from everyday practice

Prurigo nodularis (PN) is a chronic inflammatory skin disease that manifests itself as extremely itchy hard nodules. Prof. Dr. med. Dr. rer nat. Enno Schmidt from the University Hospital Schleswig-Holstein...…
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  • 6 min
  • This content is machine translated Chronic hand eczema

Changing therapy landscape – a lot is happening

Inflamed, itchy and sometimes painful skin lesions on the hands can significantly impair quality of life. If chronic hand eczema proves to be refractory to topical treatment, systemic therapy is...…
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  • 4 min
  • This content is machine translated Basic therapy for atopic dermatitis

“Emollients plus” with bacterial lysates

There are various indications in the specialist literature that the gram-negative, non-pathogenic bacterium Vitreoscilla filiformis (V. filiformis) has a beneficial effect on atopic skin. New findings confirm earlier reports of...…
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