This content is machine translated Contact eczema Causes and prevention at work Occupational groups with a high risk of developing occupational eczema include jobs with increased wet work and/or exposure to allergens. Initially, irritant hand eczema typically occurs, which can be a...… CME-Test
View Post 8 min This content is machine translated Mastocytosis Innovative pathogenesis-based therapeutic approaches in the pipeline The treatment of mastocytosis has undergone a paradigm shift in recent years. A deeper molecular understanding of the disease has paved the way from a purely symptomatic to a targeted,...…
View Post 4 min This content is machine translated Acne treatment: current trends What role do dermocosmetics play? Acne vulgaris is characterized by excessive sebum production, inflammation and impaired skin barrier function. Effective treatments should target both lesion reduction and skin hydration while being well tolerated. In this...…
This content is machine translated Hidradenitis suppurativa: biologics reduce inflammatory processes Treatment recommendations depend on the severity and inflammatory activity Due to its phenotypic heterogeneity and multifactorial pathogenesis, hidradenitis suppurativa is a complex disease that can be difficult to treat. Fortunately, research has achieved significant breakthroughs in the recent past,...…
View Post 5 min This content is machine translated Prurigo and PN Anti-inflammatory antipruritic therapy improves quality of life Which mediators are causally involved in peripheral and central itch sensitization in the context of prurigo and prurigo nodularis (PN) and contribute to the maintenance of pruritus is currently being...…
View Post 6 min This content is machine translated Atopic dermatitis: proven therapeutic principles and innovations From healthcare research to precision medicine In Switzerland, around 20 percent of children are affected by atopic eczema, compared to 4-5 percent of adults. The disease burden of AD is considerable, which is also related to...…
View Post 7 min This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has...…
View Post 8 min This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
View Post 7 min This content is machine translated Pathophysiology, clinical significance and therapeutic consequences Eosinophils in asthma For a long time, eosinophils were regarded as the central effector cells of asthma and were interpreted in the classical model as a direct damaging agent of the epithelium, as...…
View Post 4 min This content is machine translated Chronic hand eczema Topical pan-JAK-i vs. systemic retinoid: head-to-head study Alitretinoin is currently the only systemic treatment approved for severe chronic hand eczema when patients do not respond adequately to topical corticosteroids. The topical pan-Janus kinase (JAK) inhibitor delgocitinib is...…
View Post 6 min This content is machine translated Actinic keratosis Field-directed therapy methods: what the European guideline recommends Topically applied medications are a cornerstone of the field-directed treatment of actinic keratoses. In photodynamic therapy, a topical agent is combined with a procedural method. In cases of insufficient response,...…
