This content is machine translated Pancreatic Cancer Innovative early detection with a focus on liquid biopsy and AI The early detection of pancreatic cancer is developing rapidly: new multimodal approaches combine imaging with molecular biomarkers such as ctDNA, methylation signatures, fragmentomics and proteomics. For high-risk groups in particular,...…
View Post 7 min This content is machine translated Clostridioides difficile infection: specific therapy Importance of vancomycin and fidaxomicin has increased C. difficile infection (CDI) is the most common pathogen-related cause of nosocomial diarrhea, but can also occur in outpatients if risk factors are present. Due to the associated morbidity and...…
View Post 6 min This content is machine translated MASLD often goes unnoticed and is underestimated Think tank for improving the supply situation Metabolic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), can lead to serious complications. Non-invasive diagnostics and AI-supported screening have the potential to facilitate early detection in...…
View Post 4 min This content is machine translated Case series Mast cell activation syndrome (MCAS) MCAS is now understood as an independent disorder in contrast to systemic or cutaneous mastocytosis. The signs and symptoms can affect the skin, the gastrointestinal tract and the cardiovascular system,...…
View Post 9 min This content is machine translated Irritable Bowel Syndrome “Best practice” recommendations for step-by-step clarification and stage-adapted therapy The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
View Post 4 min This content is machine translated Study report Sphingolipid profile in early-stage primary biliary cholangitis Using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), a Polish research team discovered interesting new insights into the changes in sphingolipid metabolism in patients with early-stage primary...…
View Post 3 min This content is machine translated Risk of osteoporosis in autoimmune liver diseases Always determine bone density in PBC, PSC and AIH Studies show that primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are associated with a significantly increased risk of developing osteopenia or osteoporosis. For this reason,...…
View Post 6 min This content is machine translated Oncology Study updates from the ESMO Congress The variety of topics presented at the congress of the European Society for Medical Oncology (ESMO) last October underlined the breadth of the field and the close interlinking of disciplines....…
View Post 14 min This content is machine translated "Forgotten axis" between plant substances, gut and systemic health Microbiome and phytotherapy In recent years, the intestinal microbiome has developed from a marginal phenomenon to a central topic in immunology, metabolic medicine, neuroscience and oncology. Dysbiosis is associated with obesity, type 2...…
View Post 9 min This content is machine translated Microbiome, inflammaging and affective/cognitive health Gut-brain axis in old age As we age, the composition and function of the gut microbiome, the integrity of the intestinal barrier and systemic immune regulation change. These changes are closely linked to the concept...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – Sprue The term sprue is used for two different diseases that are associated with chronic diarrhea: tropical sprue and celiac disease (gluten-sensitive enteropathy), formerly known as indigenous sprue [1]. This is...…
