This content is machine translated Heart failure: combination of four as "Guideline-Directed Medical Therapy" Standard established at HFrEF with individual nuances The modern treatment of heart failure is characterized by early intervention, multidimensional care and extended therapy options. Around half of all heart failure patients have a reduced left ventricular ejection...…
View Post 7 min This content is machine translated Chronic inflammation as a driver of ageing Immunosenescence and inflammaging Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated – with consequences for susceptibility to infection,...…
View Post 8 min This content is machine translated Evidence, limitations and practical implications Phytotherapy for anxiety disorders Anxiety disorders are among the most common mental illnesses – and many sufferers want “natural” treatment options in addition to or as an alternative to conventional psychotropic drugs. For some...…
View Post 7 min This content is machine translated Modern therapeutic approaches for melanoma Innovative strategies to overcome immunotherapy resistance The therapeutic approach of immune checkpoint inhibitors has revolutionized the long-term survival of melanoma patients, but has also reached its limits. Innovative approaches such as adoptive T-cell therapy and personalized...…
View Post 7 min This content is machine translated Gonarthrosis and coxarthrosis: update on conservative treatment Pain relief, targeted movement and relief Age-associated degenerative processes in the hyaline cartilage are common. In the case of symptomatic osteoarthritis at an early stage, conservative treatment is initially sought. In addition to classification and localization...…
View Post 3 min This content is machine translated Case report: Hiccups after ketoacidosis Nebulized lidocaine brings relief Persistent hiccups are a rare but distressing symptom that can significantly affect the quality of life of patients with diabetic ketoacidosis (DKA). In one clinical case, treatment with inhaled nebulized...…
View Post 6 min This content is machine translated Hidradenitis suppurativa: biologics reduce inflammatory processes Treatment recommendations depend on the severity and inflammatory activity Due to its phenotypic heterogeneity and multifactorial pathogenesis, hidradenitis suppurativa is a complex disease that can be difficult to treat. Fortunately, research has achieved significant breakthroughs in the recent past,...…
View Post 7 min This content is machine translated Dizziness as a leading symptom: new consensus paper Current recommendations for handling in everyday practice Dizziness is one of the 20 most common causes of consultation in GP practices. Most causes of dizziness can already be clarified at the primary care level, but the broad...…
View Post 12 min This content is machine translated Endometrial carcinoma, malignant melanoma and NSCLC in focus Personalized mRNA and neoantigen vaccines in oncology mRNA technology has experienced its global breakthrough as a result of the COVID-19 pandemic and has long been clinically established. In oncology, however, the actual translation is only now beginning....…
View Post 5 min This content is machine translated Consequences for pathophysiology, clinic and therapy The inflammatory subgroup of major depression Major depression remains one of the leading causes of disability and suicidality worldwide. A key reason for the inadequate effectiveness of many treatments is their marked biological and clinical heterogeneity....…
This content is machine translated Clostridioides difficile infection: specific therapy Importance of vancomycin and fidaxomicin has increased C. difficile infection (CDI) is the most common pathogen-related cause of nosocomial diarrhea, but can also occur in outpatients if risk factors are present. Due to the associated morbidity and...…
