This content is machine translated Hidradenitis suppurativa: biologics reduce inflammatory processes Treatment recommendations depend on the severity and inflammatory activity Due to its phenotypic heterogeneity and multifactorial pathogenesis, hidradenitis suppurativa is a complex disease that can be difficult to treat. Fortunately, research has achieved significant breakthroughs in the recent past,...…
View Post 7 min This content is machine translated Dizziness as a leading symptom: new consensus paper Current recommendations for handling in everyday practice Dizziness is one of the 20 most common causes of consultation in GP practices. Most causes of dizziness can already be clarified at the primary care level, but the broad...…
View Post 12 min This content is machine translated Endometrial carcinoma, malignant melanoma and NSCLC in focus Personalized mRNA and neoantigen vaccines in oncology mRNA technology has experienced its global breakthrough as a result of the COVID-19 pandemic and has long been clinically established. In oncology, however, the actual translation is only now beginning....…
View Post 5 min This content is machine translated Consequences for pathophysiology, clinic and therapy The inflammatory subgroup of major depression Major depression remains one of the leading causes of disability and suicidality worldwide. A key reason for the inadequate effectiveness of many treatments is their marked biological and clinical heterogeneity....…
View Post 3 min This content is machine translated Adherence of GLP1-RA Half of patients discontinue treatment within a year GLP1 receptor agonists have revolutionized the treatment of obesity, but their effectiveness depends on long-term and continuous use. However, data from Danish health registries presented at EASD 2025 show that...…
View Post 4 min This content is machine translated Acne treatment: current trends What role do dermocosmetics play? Acne vulgaris is characterized by excessive sebum production, inflammation and impaired skin barrier function. Effective treatments should target both lesion reduction and skin hydration while being well tolerated. In this...…
View Post 6 min This content is machine translated COPD: Tailor therapy to individual characteristics Risk of exacerbation correlates with the eosinophil count and other factors The severity of COPD is determined based on lung function values, exacerbation history and symptom burden. A triple combination with inhaled steroids (ICS) is recommended for patients with a high...…
View Post 7 min This content is machine translated Focus on new therapeutic targets and senolytics Cellular senescence Cellular senescence is considered a key biological program that can exert both protective and potentially pathogenic effects in tissues across the lifespan. If senescent cells persist, they are associated with...…
View Post 3 min This content is machine translated Development of a quintuple agonist New strategy in the fight against obesity and T2D The treatment of obesity and type 2 diabetes is increasingly shifting to newer incretin drugs, including GLP1 receptor agonists (single agonists such as semaglutide) and GIP- and GLP1-RA (dual agonists...…
View Post 7 min This content is machine translated Arterial elasticity, vascular ageing, endothelial function Longevity and cardiovascular health 2025 Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
View Post 5 min This content is machine translated AI-supported risk stratification for chest pain in the emergency room Performance of a fully automated ECG model Despite guidelines, the standardized assessment of chest pain in the emergency department remains inconsistent, expensive and prone to misinterpretation. A retrospective two-center study approach published in Open Heart now presents...…
