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  • IBD matters: Module four

Molecular mechanisms in pathogenesis and treatment.

    • Allergology and clinical immunology
    • CME continuing education
    • Gastroenterology and Hepatology
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  • 11 minute read

This content is machine-translated. Please contact us if you need professional translation services.

Studies have shown that altered immune cell transport and pathogenic immune cells are critical factors responsible for mucosal inflammation and tissue destruction in IBD. A defective intestinal barrier and microbial dysbiosis lead to such accumulation and local activation of immune cells, resulting in a pro-inflammatory cytokine loop that overrides anti-inflammatory signals and causes chronic intestinal inflammation.

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Partner
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Autoren
  • Prof. Dr. med. Michael Scharl
  • Prof. Dr. med. Markus F. Neurath
Publikation
  • HAUSARZT PRAXIS
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