Polygenic risk score can help identify COPD

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in patients worldwide and yet often goes undiagnosed. Although genetic risk plays a significant role in susceptibility to COPD, it is unclear whether it is helpful in performing spirometry tests and identifying undiagnosed cases. American researchers investigated whether a polygenic risk score improves the identification of undiagnosed COPD beyond the conventional approach to case finding.