This content is machine translated Acute otitis media: self-limiting course vs. "red flags" In which cases are antibiotics necessary? Otoscopic evaluation of the eardrum is crucial to diagnose acute otitis media. This is a very common and usually self-limiting infection in children. The quintessence of current guideline recommendations is...…
View Post 10 min This content is machine translated Patients with leg swelling DVT and other common DDs with peripheral edema Swelling of the lower extremities is common, especially in older adults. Due to the complex interrelationships, the clarification of such findings in general practice is a challenge. The differential diagnostic...…
View Post 4 min This content is machine translated Study report Sphingolipid profile in early-stage primary biliary cholangitis Using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), a Polish research team discovered interesting new insights into the changes in sphingolipid metabolism in patients with early-stage primary...…
View Post 6 min This content is machine translated Abdominal aortic aneurysms in primary care Risk-stratified screening and prophylaxis As abdominal aortic aneurysms are usually asymptomatic but potentially life-threatening, patients at risk should be screened in a targeted manner. These include in particular men over 65 and patients with...…
View Post 6 min This content is machine translated Angiosarcoma of the heart A diagnostic and therapeutic “black box” Primary angiosarcomas of the heart are among the rarest and most aggressive malignant tumors. The unspecific symptoms, rapid progression and complex differential diagnosis make early detection considerably more difficult. Despite...…
View Post 5 min This content is machine translated Ataxias Friedreich’s ataxia: when the energy metabolism attacks the nervous system Energy deficiency instead of pure oxidative stress: New data show that in Friedreich’s ataxia, disturbances in fatty acid and ketone body metabolism in particular contribute to selective neurodegeneration. The article...…
View Post 3 min This content is machine translated Risk of osteoporosis in autoimmune liver diseases Always determine bone density in PBC, PSC and AIH Studies show that primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are associated with a significantly increased risk of developing osteopenia or osteoporosis. For this reason,...…
View Post 3 min This content is machine translated Neuroendocrine tumors Precision medicine in diagnostics and therapy Thanks to modern imaging and molecular characterization, neuroendocrine tumours can now be detected and classified in a much more targeted manner. New therapeutic procedures such as radioligand therapy and targeted...…
View Post 3 min This content is machine translated Case report: Complication after type 2 diabetes Topical corticosteroids lead to ketoacidosis Hyperglycemic crises due to topical corticosteroid use are extremely rare. In this case report, however, physicians were faced with an unusual case of diabetic ketoacidosis (DKA) triggered by the postoperative...…
View Post 6 min This content is machine translated Multimorbidity and functional capacity in old age Clarify individual health status and reduce risks The term “frailty” describes the state of increased vulnerability to an unfavorable health outcome and includes, among other things, falls, acute confusion (delirium) and restrictions in functional skills relevant to...…
View Post 12 min This content is machine translated NSCLC Bispecific antibodies for rare EGFR mutations Rare EGFR mutations such as exon 20 insertion changes have long been considered a therapeutic dead end in non-small cell lung cancer (NSCLC). Current data show that innovative mechanisms of...…
