Many patients with inflammatory bowel disease (IBD) suffer from disease-associated symptoms outside the gastrointestinal tract. Classic extraintestinal manifestations (EIM) that may occur in association with IBD include rheumatologic, ocular, cutaneous, and hepatobiliary symptoms. The most common EIM are rheumatologic conditions (peripheral arthritis, spondyloarthritis). Anemia is one of the most common comorbidities in patients with IBD. Therefore, this should also be clarified during follow-up and, if necessary, treated by means of iron substitution therapy.